The Empowering Neurologist Podcast

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Today on The Empowering Neurologist podcast we are going to explore PTSD, post traumatic stress disorder, a pervasive issue that can be profoundly debilitating. PTSD is experienced by about 6% of the US population at some point in their lifetime and at any given time approximately 5% of American adults are living with this disorder. Certainly, we see high risk and veterans with PTSD affecting about 11 to 20% of veterans who served in operations Iraqi Freedom and Enduring Freedom. Vietnam veterans experience a lifetime prevalence somewhere in the neighborhood of 30%. PTSD symptoms usually begin within three months of a traumatic event, but can actually surface many years later making the diagnosis and the relationship to a traumatic event challenging. In about 1/3 of cases, PTSD becomes chronic and can last for years or even decades. We know that there are significant comorbidities associated with PTSD, including other mental health conditions like depression or anxiety disorder, substance use disorders, and even cognitive decline. While cognitive behavioral therapy, CBT, and pharmaceutical intervention are the “go to” treatments for this problem, hyperbaric oxygen therapy presents us with a new and emerging therapy now receiving global recognition. We will review research on this podcast demonstrating the profound effectiveness of hyperbaric oxygen in treating PTSD, research that makes it clear that this is one of the most powerful interventions ever developed for treating this challenging disorder. We will visit the Aviv Clinic in Central Florida, and spend time with Dr. Mohammad Elamir. ==== 0:00 Intro 4:55 Why Hyperbaric Works for PTSD Patients 8:44 Evaluating patients with PTSD 12:30 How the Protocol Was Chosen & Implemented 16:40 Potential Side Effects 18:00 Youngest People Treated with This 19:32 Combining Therapy Modalities for PTSD 20:14 Other Conditions that Can Be Helped By This 22:04 Amazing Results From These Studies 24:06 Using this with Our Military 26:00 Getting to the Root Problems 26:48 Treating Traumatic Brain Injuries 28:54 Why This Isn’t More Widely Being Offered 29:49 The Right Formula for This 32:55 Get Involved Today ==== Dr. Mohammed Elamir, or “Dr. Mo”to his patients, has been part of the Aviv Clinics team in The Villages since the clinic opened in 2020. As lead physician, he oversees the medical treatment for all clients in the Aviv Medical Program, collaborating with other members of Aviv’s clinical team to provide truly comprehensive care. As a presenter, his seminars often sell out, thanks in part to his ability to translate complex scientific concepts and data into easily-relatable language. Prior to joining Aviv Clinics, Dr. Elamir practiced internal medicine at the MM Jersey Breathing Center while also owning a medical spa in New Jersey. He completed his internal medicine internship and residency at RWJ-Barnabas: Jersey City Medical Center where he was chief resident and a member of the ethics committee. Dr. Mo has a passion for helping others who are pursuing a career in medicine and continues to mentor pre-med and medical school students. Dr. Elamir became involved with Aviv Clinics after his late father suffered a stroke, which sparked Dr. Mo’s interest in novel approaches to healing the brain. He is the father of two children, including a son with autism spectrum disorder (ASD). Dr. Elamir considers it his life’s mission to help progress his son’s development and better understand the causes and treatment of ASD. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 In this compelling episode of The Empowering Neurologist, I sit down with Dr. Ray Dorsey, a leading voice in the world of neurology and author of the important new book, The Parkinson’s Plan. Dr. Dorsey is a passionate advocate for changing how we view and address Parkinson’s disease. His message is bold—and urgently needed: Parkinson’s is not simply a disease of aging or bad luck. It is, in his words, “a man-made disease,” driven by preventable environmental exposures. Dr. Dorsey’s work shines a much-needed spotlight on the role of toxins in triggering Parkinson’s. In his new book, he lays out a comprehensive framework for understanding and reversing the rising tide of Parkinson’s cases, which have more than doubled in recent decades. He argues that this surge is no coincidence—it correlates with increased exposure to industrial chemicals, pesticides, and air pollutants that interfere with the brain’s delicate dopamine system. One of the most striking recent contributions from Dr. Dorsey’s research is a JAMA-published study linking Parkinson’s risk to proximity to golf courses—locations that are frequently treated with high volumes of chemical herbicides and pesticides. The study found a significantly increased risk of developing Parkinson’s disease in individuals living near these manicured greens. This adds to a growing body of evidence that toxic environmental exposures play a key role in the development of this neurodegenerative condition. In our conversation, Dr. Dorsey discusses how Parkinson’s (once a rare disease) has become the world’s fastest-growing brain disorder, and why its rise can’t be explained by aging populations alone. He shares practical strategies for individuals and families looking to reduce their toxic burden and offers hope for a new paradigm. One in which we actively prevent, treat, and ultimately aim to eliminate Parkinson’s. Try Lichen Air, an air filter carefully constructed to remove the maximum amount of PM 2.5 and smaller air pollutants possible: https://lichenair.com/ ==== 0:00 Intro 2:40 Living Near to a Golf course Raises Parkinson’s Risk 4:58 How Pollutants Lead to Parkinson’s 7:12 Danger of Dry cleaning Chemicals 11:45 Parkinson’s is not just about Genetics 14:15 Why aren't these chemicals illegal? 17:07 Toxicity of Weed Killer 21:00 Chemicals that Damage Mitochondria 26:39 Why Diabetes Increases Parkinson’s Risk 29:38Air Pollution & WildFires 34:04 The Air Purifier We Recommend 34:49 Dealing with Indoor Air Pollution 37:02 Wash All Produce (Even Organic) 38:12 Best Diet for Parkinson’s Prevention 41:26 Safe Practices for Farming & Dry Cleaning 45:23 Benefits of Exercise 48:01 Public Figures Who Faced Parkinson's Disease 49:58 Why Men are More Likely to Get It 51:21 An Empowering Message for Us 54:27 Conclusion ==== Dr. Ray Dorsey is the director of the Center for the Brain & the Environment at the Atria Health and Research Institute. The center’s mission is to identify the root causes of brain diseases from autism to Alzheimer’s so that we can prevent them. With his colleagues, he wrote Ending Parkinson’s Disease and the forthcoming The Parkinson’s Plan, which details a new path to preventing and treating this terrible disease. Ray previously directed the Center for Health + Technology at the University of Rochester, chaired the international Huntington Study Group, led the movement disorders division at Johns Hopkins, and consulted for McKinsey & Company. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 I’m thrilled to announce this exciting podcast episode featuring an inspiring and thought-provoking conversation with Dr. Mai Nguyen, CEO and Co-founder of OptoCeutics. Dr. Nguyen is a pioneering force in the field of neurotechnology, and in this episode, we unpack her revolutionary work using non-invasive light stimulation to enhance brain function and potentially prevent neurodegenerative disease. At the center of our conversation is the EVY, a 40 Hertz light stimulation device developed by OptoCeutics under Dr. Nguyen’s leadership. This device is designed to target and enhance gamma oscillations in the brain—a specific frequency range of neural activity (around 40 Hz) that is critically involved in memory, attention, and perception. In recent years, scientific studies have linked disruptions in gamma oscillations with the progression of Alzheimer’s disease. By restoring these rhythms, the EVY device aims to provide a non-pharmacological, non-invasive way to support brain health. During our podcast, Dr. Nguyen explains how EVY works: the device emits flickering light at a precise 40 Hz frequency, which is thought to entrain brain activity to resonate at that same frequency. This gentle stimulation may help reduce amyloid-beta accumulation, improve neural connectivity, and promote immune system engagement in the brain—mechanisms that could slow or even reverse aspects of cognitive decline. What sets Dr. Nguyen apart is not just her scientific brilliance, but her deep commitment to translating research into real-world solutions. She leads OptoCeutics with a clear mission: to bring accessible, evidence-based neurotechnology into homes and clinics, empowering people to take charge of their cognitive well-being. Her approach is both deeply human and rigorously scientific, blending innovation with empathy. As you’ll hear in the interview, Dr. Nguyen's work exemplifies the exciting convergence of biology, technology, and therapeutic application. This episode is essential listening for anyone interested in the future of brain health, the science of neuroplasticity, and the promise of light-based therapies. Whether you're a clinician, researcher, caregiver, or simply curious about how to support your brain as you age, Dr. Nguyen’s insights will leave you informed, inspired, and hopeful. ==== 0:00 Intro 2:46 How Dr. Mai Started Studying it 5:16 How Light Enhances Gamma Oscillation 7:22 Promise of These Studies 8:51 How the EVY Device Works 11:20 Early Clinical Results + Potential Side Effects 13:53 Application of this technology 16:36 Why Mainstream is Late to Adopt This 22:04 Impact of Auditory Stimulation 23:38 The Future of This Research 25:25 Get Involved Today ==== Dr. Nguyen is a trailblazer in neurotechnology, pioneering advancements in non-invasive brain stimulation technology for the prevention and treatment of Alzheimer’s and dementia. As CEO and Co-founder of OptoCeutics, Dr. Nguyen leads the charge in bridging the gap between neuroscience and therapeutic innovation, offering new hope to millions affected by cognitive decline. Under Dr. Nguyen’s leadership, Optoceutics has become a frontrunner in brain stimulation technology and a recognized authority in non-invasive neuromodulation. Her unique approach combines rigorous scientific methodology with groundbreaking therapeutic solutions. This vision is shaped by her academic excellence, including a PhD in Integrative Biology at the University of California, Berkeley with a specialization in Neuroendocrinology, and her extensive training in management, technology innovation, and entrepreneurship. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our...

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 In our modern world, we are surrounded by a staggering number of invisible threats. These chemicals and pollutants can silently undermine our immune systems, increase our risk for chronic illness, and sabotage our health at the cellular level. That’s why I’m especially excited to welcome Dr. Aly Cohen to this episode of The Empowering Neurologist. This conversation is not only eye-opening, it’s empowering and filled with practical, actionable steps that each of us can take starting today. In our conversation Dr. Cohen takes us through the science and the soul of her mission. We explore what inspired her to write Detoxify, a journey that began at the intersection of clinical frustration and personal awakening. Over the years, she began noticing that many of her patients with autoimmune diseases, chronic fatigue, hormonal imbalances, and neurological complaints shared a common thread: consistent exposure to environmental toxins. This wasn't just about vague “bad stuff.”Dr. Cohen has zeroed in on a specific category of chemicals she terms “Immune-disrupting chemicals (IDCs).” These are substances that directly interfere with the immune system's ability to regulate and repair. Dr. Cohen doesn’t stop at theory… she gets specific - with personal care products to avoid, water purification tips every household should know, and simple DIY recipes for safer cleaning and skincare. Her “Detoxify Food Pyramid” reimagines what a clean, immune-supportive diet looks like in a world of processed foods and contaminated agriculture. We also touch on how environmental toxins can act as potent triggers for autoimmune conditions like lupus and rheumatoid arthritis - diseases Dr. Cohen treats in her clinical practice almost every day. If you’re feeling overwhelmed by the sheer scale of modern toxicity, this episode offers a clear and hopeful path forward. Dr. Cohen emphasizes that detoxifying your life doesn’t mean doing everything at once. It’s about starting small. Things like switching to a glass water bottle, choosing fragrance-free detergents, and reading ingredient labels can lead to profound health benefits. ==== TIMESTAMPS 00:00 Introduction 02:15 Welcoming Dr. Amy Cohen & Her Inspiration for Her Book 05:45 Water & How Contamination Dysregulates Our Immune System 10:44 Recommendations for Filtration and Purification 13:13 Quality of Bottled Water Is Sub Par & Likely Tap Water 18:03 Endocrine Disrupting Chemical Contaminants Found In Our Water 21:47 Sparking Change with The Four A's: Assess, Avoid Or Swap, Add, Allow 27:39 How Did These Chemicals Enter Our Food & Water Supply? 34:10 How Do Genetics Determine Your Ability To Detoxify? 37:50 Air Quality, Pollution, and The Impact On Our Bodies 43:49 Navigating How To Improve The Air You Breath 47:41 Detoxifying The Body From Air Pollution 51:18 Hidden Threats In Your Personal Care Products & How To Avoid Them 1:04:19 Conclusion ==== Dr. Aly Cohen is a board-certified physician practicing in rheumatology and integrative medicine, as well as an environmental health expert in Princeton, New Jersey. Her new book, DETOXIFY: The Everyday Toxins Harming Your Immune System and How to Defend Against Them, available now for preorder, connects the dots between everyday chemicals and the epidemic rise in immune disorders and autoimmune disease...and what we CAN all do about it! You can follow her health and wellness tips and recommendations on Facebook at The Smart Human, Twitter, and Instagram: @thesmarthuman, and TikTok. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 The ketogenic diet has become a household term, often associated with rapid weight loss and an effective means of shedding stubborn fat. However, as my guest on this episode of The Empowering Neurologist, Dr. Dominic D’Agostino, will explain, there is so much more to the ketogenic lifestyle than simply dropping a few pounds. We’re diving deep into the science of metabolism, insulin sensitivity, and how our lifestyle choices impact long-term health, particularly brain health. While many people adopt a ketogenic diet for its well-documented benefits in weight management, its effects on metabolism reach far beyond simple fat burning. Nutritional ketosis helps the body transition from relying primarily on carbohydrates for energy to efficiently burning fat and producing ketones, an alternative fuel source for the brain and muscles. As Dr. D’Agostino will discuss, one of the most crucial aspects of metabolic health is insulin sensitivity. When insulin function is compromised, the body struggles to regulate blood sugar levels, leading to increased risks of obesity, type 2 diabetes, and even cognitive decline. By keeping insulin sensitivity in check through dietary choices, fasting, and exercise, we can enhance our metabolic health and lower the risk of chronic disease. The brain is an energy-intensive organ, and its function is directly influenced by our metabolic state. Research has shown that ketones provide a more efficient and neuroprotective fuel source for the brain compared to glucose. This is particularly relevant for conditions such as Alzheimer’s disease, epilepsy, and even traumatic brain injury. By making intentional choices about what we eat, how we move, and how we recover, we can take control of our metabolic health and improve our longevity. ==== 00:00 Introduction 02:21 How Dr. D’Agostino Went From Seizure Research To Nutrition Science 03:31 From Drug Failures To The Medical Power Of Ketosis 05:15 What Ketones Really Are And Why They’re A Metabolic Game-Changer 09:37 Why Ketogenic Therapy Is Now In 400+ Clinical Trials Worldwide 12:21 GLP-1 Drugs, Weight Loss, And Keto: What They Do To Your Metabolism 15:10 Inside A Ketogenic Body: Fat Burning, Fuel Switching, And More 17:25 How Lowering Insulin Turns On Fat Burning And Ketone Production 20:03 Why Ketones Keep The Brain Stable And Cravings Under Control 23:54 The Right Amount Of Protein For Muscle, Aging, And Staying In Ketosis 27:03 Do You Actually Need Fiber? The Carnivore Diet And Gut Health 30:00 How Ketosis Reduces Inflammation And Repairs The Gut Barrier 34:31 Genomics of Ketonics: Beta-Hydroxybutyrate’s Epigenetic Power 45:38 Allulose: The Sweetener That Lowers Blood Sugar And Boosts GLP-1 52:03 Why MCT Oil Might Be The Most Underrated Keto Hack Available 54:30 Conclusion ==== Dominic D’Agostino, Ph.D., is a tenured Associate Professor at the University of South Florida (USF) Morsani College of Medicine in the Department of Molecular Pharmacology and Physiology. He teaches medical neuroscience, medical physiology, nutrition and neuropharmacology. He is also a Senior Visiting Research Scientist at the Institute for Human and Machine Cognition (IHMC) to assist with their efforts towards optimizing the safety, health and resilience of the warfighter and astronaut. His primary research focuses on developing and testing nutritional and metabolic-based therapies for a variety of disease states and advancing the use of metabolic-based therapies into human clinical applications. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Cancer remains a formidable global challenge, with nearly one in six deaths worldwide attributed to the disease. Over 60% of patients undergoing conventional treatments experience severe side effects, highlighting the need for complementary therapies that enhance efficacy and reduce harm. Dr. Valter Longo, a leading figure in aging and nutritional science, has introduced a groundbreaking approach known as the fasting mimicking diet (FMD). Through years of research, Dr. Longo has shown that cycles of controlled fasting can trigger cellular regeneration, reduce inflammation, and improve metabolic health. His work has reshaped our understanding of nutrition’s role in health and disease, providing a scientific basis for fasting as a tool to support standard cancer therapies. The fasting mimicking diet offers a promising adjunct to traditional treatments. By strategically reducing calorie intake, FMD protects healthy cells and makes cancer cells more vulnerable to chemotherapy and radiation. This dual effect boosts the effectiveness of treatment while mitigating debilitating side effects. Dr. Longo’s new book, Fasting Cancer, the subject of our podcast, explores the science behind fasting and its potential to transform cancer care. He shares practical guidelines, compelling case studies, and robust research that illustrate how FMD can be integrated with standard therapies for better outcomes. Listeners of The Empowering Neurologist were captivated by Dr. Longo’s ability to translate complex science into actionable advice in his previous appearance, and this episode is no exception. His work continues to inspire both patients and healthcare professionals to explore innovative, science-driven approaches in the fight against cancer. As research unfolds, the fasting mimicking diet stands as a testament to the power of nutritional science in modern medicine. Embracing this strategy, patients and clinicians alike are witnessing a promising future in cancer care. ==== 00:00 Introduction 02:10 The Cancer Nutrition Scientist Changing Everything 04:36 How Cancer Cells Hack Aging And Stay Immortal 06:00 The Hidden Danger Of Cancer Cell Survival After Chemo 07:30 Why Young People Are Getting More Cancer Than Ever 10:48 Are We Eating Too Much Protein For Longevity 13:22 A Diet That Weakens Cancer But Shields Healthy Cells 17:55 What Is The Fasting Mimicking Diet And Why It Works 21:40 The Critical Timing That Makes Chemo More Effective 23:00 How Starving Cancer Creates A Predictable Weak Spot 27:30 The Multi-Angle Attack That Slows Glioblastoma 29:15 Could This Diet Delay Or Reverse Alzheimer’s 32:50 Clinical Trials Show This Diet Reverses Diabetes 36:30 How Fasting Triggers Organ Regeneration In Humans 41:05 The Shocking Risks Behind Popular Weight Loss Drugs 57:14 Conclusion ==== Valter Longo is the director of the Longevity Institute at the University of Southern California in Los Angeles. He studies basic and clinical research on nutrition, aging, and disease, with a focus on cancer, autoimmunity, Alzheimer’s, and cardiometabolic illness. Dr. Longo has received multiple awards including the 2010 Nathan Shock Lecture Award from the National Institute on Aging, the 2013 Vincent Cristofalo Rising Star Award, and the 2016 Glenn Award for Research in the Biological Mechanisms of Aging. In 2018, Time named him one of the 50 most influential people in health care, and in 2021 Science magazine called him a pioneer in nutrition and cancer. He is the author of Fasting Cancer and The Longevity Diet. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Welcome back to The Empowering Neurologist! In this episode we have a truly fascinating conversation lined up with none other than Dr. Steven Gundry, a world-renowned heart surgeon-turned-functional medicine expert, whose work has transformed the way we understand diet, disease, and longevity. Dr. Gundry is no stranger to challenging conventional medical wisdom. In his latest book, The Gut-Brain Paradox: Improve Your Mood, Clear Brain Fog, and Reverse Disease by Healing Your Microbiome (HarperCollins; April 15, 2025), he flips the script on the traditional gut-brain connection. His research reveals a startling truth: your microbiome is not just influencing your brain—it’s controlling it. For years, we’ve heard that the brain sends signals to the gut. But Dr. Gundry shows that it’s actually the other way around: the microbes in our gut are shaping our thoughts, emotions, and even personality. From food cravings to mental health struggles, from cognitive decline to addiction—these tiny gut-dwelling organisms are the real puppet masters. And when our gut falls out of balance, neurological dysfunction follows. In this episode, we’ll explore: ✅ How gut bacteria influence cravings, mood, and even personality ✅ The surprising link between gut inflammation and drug tolerance ✅ Why a leaky gut can lead to brain fog, neurodegeneration, and mental health issues ✅ How to reclaim control of your mind by healing your microbiome Dr. Gundry lays out a powerful, science-backed plan to restore gut health and optimize brain function, mental clarity, and emotional well-being. If you’ve ever struggled with brain fog, anxiety, depression, or unexplained neurological symptoms, this episode is a must-listen. Tune in to this eye-opening conversation and discover how fixing your gut provides an important step to unlocking your brain’s full potential. ==== 00:00 Introduction 03:00 Why a Heart Surgeon Wrote a Book on the Brain 06:18 The Forgotten Hero Who Was Beaten to Death for Washing His Hands 09:08 A Parkinson’s Case Reversed by Healing the Gut? 13:28 Gluten Cross-Contamination and a Son’s Cutting Board: A Shocking Relapse 19:16 Gut Leaks, Brain Barriers, and Immune Sabotage: The Mechanism Explained 23:15 The Alzheimer’s Barrier Theory: Why Beta-Amyloid Might Be the Brain’s Defense System 26:20 Can Depression Be Healed Through the Gut? 30:27 Are Bacteria Controlling Your Addictions and Cravings? 34:02 The Scariest Mind-Control Parasite You’ve Never Heard Of 38:41 Eat This, Not That: How to Hack Your Gut for Better Brain Health 41:23 Neu5Gc and How it Impacts Our Brains 48:03 Are Polyphenols the Brain’s Secret Weapon? 56:38 Dead Bacteria, Live Benefits: Why Your Probiotic Doesn’t Need to Survive 01:05:05 Conclusion and Thank you ==== Steven R. Gundry, MD, is the director of the International Heart and Lung Institute in Palm Springs, California, and the founder and director of the Center for Restorative Medicine in Palm Springs and Santa Barbara. After a distinguished surgical career as a professor and chairman of cardiothoracic surgery at Loma Linda University, Dr. Gundry changed his focus to curing modern diseases via dietary changes. He has written more than three hundred articles published in peer-reviewed journals on using diet and supplements to eliminate heart disease, diabetes, autoimmune disease, and multiple other diseases. He is the host of the top ranked nutrition podcast The Dr. Gundry Podcast and founder of Gundry MD, a wellness brand. Dr. Gundry lives with his wife, Penny, and their dogs in Palm Springs and Montecito, California. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 We hear so much these days about various “biohacking” techniques that are purported to be helpful for us in terms of improving our health and even extending our lifespan. But I think it's really important that we unpack some of these ideas and get a good understanding as to what they involve and what we can expect if we were to engage them. We're going to explore a variety of hot topics like exosome therapy, peptide therapy, cryotherapy hyperbaric oxygen therapy, and other innovative techniques. But most importantly we will explore how our simple, day-to-day lifestyle choices impact our health in terms of preserving our resistance to disease, and possibly even extending our lives. Our guest is Dr. Darshan Shah, a powerful influencer in the area of health-span improvement. Let me tell you a little bit more about Dr. Shah.Darshan Shah, MD, is a health and wellness specialist, board-certified surgeon, published author, entrepreneur, and founder of Next Health, the world's first and largest Health Optimization and Longevity clinic. As a Longevity Medicine specialist, he has advised thousands of patients on how to optimize their well-being and extend their healthspan and lifespan. Dr. Shah began his career at an accelerated MD program and earned his medical degree at the age of 21, becoming one of the youngest doctors in the United States. He continued his training at the Mayo Clinic, one of the most prestigious medical institutes in the country. Dr. Shah’s belief in continual education and self-improvement has earned him alumni status at Harvard Business School, Singularity University, and other prestigious institutions. His passion is speaking on the topics of longevity and health, having done over 100+ speaking engagements and appearances. 0:00 Intro 2:52 How Dr. Darshan Shah Began Studying Longevity 9:14 The Next Health Clinic: Cutting-Edge Longevity Science 12:11 The Biggest Health Mistake People Don't Realize 14:47 Evaluating Biomarkers & Their Clinical Importance 20:52 Key Biomarkers to Monitor Inflammation & Uric Acid 23:43 Why Uric Acid Matters 25:32 Clarifying the Confusion Surrounding Cholesterol 29:20 Hormone Levels as a Key Marker of Health (TRT) 35:22 Cutting Edge Science: Peptide Therapy 41:54 The Success of These Treatments 43:05 Science of Exosome Therapy 44:55 NAD & Stimulating the Mitochondria 46:41 Effectiveness of Cryotherapy 48:19 How Mainstream Physicians View this Approach 50:37 Cognitive Decline 52:09 His #1 Health Practice for Longevity 53:40 Conclusion ==== Dr. Darshan Shah is a health optimization expert, board-certified surgeon, and founder of Next Health, the world’s first Health Optimization and Longevity clinic. A graduate of an accelerated MD program, he earned his medical degree at 21 and trained at the Mayo Clinic. With over 20,000 surgeries performed and multiple ventures in the wellness space, Dr. Shah now focuses on helping people extend their healthspan through cutting-edge science and personalized care. He’s also a sought-after speaker and lifelong learner with credentials from Harvard Business School and Singularity University. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com The idea that we can live however we want and then rely on a magic treatment for cognitive issues is unrealistic and dangerous. The reality is that our daily choices profoundly impact our brain’s future, and once cognitive decline begins, there is no clear-cut pharmaceutical solution. I had the pleasure of speaking with Dr. Dale Bredesen, whose book The Ageless Brain is an incredible resource for protecting brain health. He has pioneered a comprehensive approach to preventing and even reversing cognitive decline. This book offers a powerful blueprint not only for sharpening your mind but also for building resilience against neurodegenerative diseases. In The Ageless Brain, Dr. Bredesen distills decades of research into actionable steps. He explores key lifestyle factors—nutrition, sleep, exercise, stress management, and supplementation—that influence cognitive performance and long-term brain resilience. What’s exciting is his proactive, personalized approach. Rather than waiting for symptoms to appear, Dr. Bredesen shows us how to build a brain that resists aging from the start. Today, we’ll unpack some of the most impactful strategies from his book, discuss major breakthroughs in neuroscience, and explore how we can all take charge of our cognitive health. If you’ve ever wondered what it takes to maintain lifelong clarity and vitality, you won’t want to miss this conversation. Dale Bredesen, MD, is an internationally recognized neurologist specializing in neurodegenerative diseases. He is the Senior Director of Precision Brain Health at Pacific Neuroscience Institute® and the Chief Scientific Officer at Apollo Health. Guided by his belief that Alzheimer’s is not just preventable but reversible, Dr. Bredesen’s groundbreaking research has helped explain the biological mechanisms behind memory loss. His decades of study have led to new treatment approaches, including the ReCODE Protocol™—also known as the Bredesen Protocol—a strategy designed to prevent, slow, and even reverse cognitive decline associated with Alzheimer’s, dementia, and mild cognitive impairment. Timestamps: 0:00 Introduction to Guest 2:48 Phase 3 Trial Upcoming 10:11 Alzheimer’s: Different Triggers, Different Outcomes 13:11 Could Brushing Your Teeth Save Your Brain? (Oral Microbiome & Alzheimer’s 18:45 The 3 Major Players in Brain Health 22:24 How to Make Sure You Never Get Dementia 22:33 Blood Markers for Alzheimer’s: What Your Tests Reveal 28:10 Diabetes and Alzheimer’s: The Hidden Connection 34:18 The #1 Contributor to Cognitive Decline: Insulin Resistance 39:54 How to Match Your Brainspan to Your Lifespan 40:31 Top Supplements for Brain Health 43:15 The Power of Nitric Oxide for Your Brain 48:07 Leaky Gut & Cognitive Decline 54:15 Metformin & Brain Longevity 57:31 Why Do More Men Than Women Get Parkinson’s 1:05:24 ADHD & Alzheimer’s: The Fruit Fly Discovery ("Alzflymers") ___________________________ Dale Bredesen, M.D., is an expert in neurodegenerative diseases such as Alzheimer’s. He is a graduate of Caltech and received his MD from Duke University Medical Center. His career includes serving as Chief Resident in Neurology at UCSF, working as an NIH Postdoctoral Fellow, and holding faculty positions at UCSF, UCLA, and UC San Diego. He was the director of the Program on Aging at the Burnham Institute and the founding President and CEO of the Buck Institute. His work has led to a new therapeutic approach for treating Alzheimer’s. He is the author of The End of Alzheimer’s: The First Program to Prevent and Reverse Cognitive Decline. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Yes, we need stress in our lives! Staying in our comfort zone may be doing us more harm than good. That’s probably surprising to hear from me having spoken about the importance of reducing stress over the years. But, nonetheless, a level of stress that is not overly damaging, and that may actually have positive benefits. Today we are going to learn much more about that will be looking at the book, The Stress Paradox with Dr. Sharon Horesh Bergquist. We're going to learn about the"Stress dilemma" that we face, how stress enhances, cellular resilience, how our life compares to the lives of our ancestors in terms of the physical stresses that we endure. We will explore how stressing ourselves in relation to the times that we eat, our physical exercise, and even explore how sleep or lack of sleep, may affect us in negative and even perhaps positive ways. All in all, we"re learning these days how we want to do our best to leverage the value of being out of our comfort zone but also recognizing our boundaries. 00:00 Introduction 02:00 Welcoming Sharon and Introducing The Stress Paradox 06:33 Sleep is Critical 07:12 Good Stress (HIIT) vs. Bad Stress (Financial Hardship) 09:50 Hormetic Stress? Current Environment vs. Ancestors' Stress Levels 13:20 Stress Responses Stored in Phytochemicals and our Evolutionary Relationship with Plants 19:01 10,000 DNA Injuries Any Given Day, 7 Per Minute 22:03 The Biggest Factor Related to Longevity 26:01 Relationship with Decreased Risk of Alzheimer’s & The Role of Myokines 30:17 Microglia Cells Can Share Mitochondria (Before & After) 35:13 Heat Exposure Mimics the Benefits of Exercise 38:01 Key Strategies for Longevity and Vitality 45:32 Personalized Health Strategies for Optimal Performance 50:25: The Cortisol Spike and Why It is Necessary 58:20 Why You Need Non-negotiables In Your Physiology 50:20 Conclusion ==== Sharon Horesh Bergquist, MD, is an award-winning physician, innovative healthcare leader, and visionary researcher renowned for spearheading a science-based approach to applying lifestyle as medicine. She has helped lead numerous clinical trials, including the Emory Healthy Aging Study and the NIH funded Emory Healthy Brain Study. Dr. Bergquist is widely published in peer-reviewed journals and has contributed to over 200 news ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 We all want to live a stress-free life. But as it turns out, this may not necessarily be in our best interest having a low level of stress of various types turns out to be good for our physiology and can even help us recover from illness. When stress is implemented in this way, it is termed, other words, the upside of low-grade stress. That stress can be exercise, immersion ourselves in cold or hot temperatures, time restricted eating, or even various forms of light exposure all of which we will explore on my podcast today, which is an interview with my good friend, Jeff Krasno. His new book, Good Stress, that he wrote along with his wife Schuyler Grant He is the CEO and founder of Commune Media, a masterclass platform for well-being that features renowned authors and teachers. He hosts the Commune podcast, which has over 520 episodes and generates more than 750,000 monthly downloads, featuring interviews with luminaries such as Deepak Chopra, Marianne Williamson, Matthew McConaughey, and Gabor Maté. Additionally, Jeff writes a weekly "Commusing" essay exploring well-being, spirituality, and culture, distributed to an email list of over one million subscribers. Prior to founding Commune Media, Jeff co-created Wanderlust, a global series of wellness events that have significantly contributed to popularizing yoga practices and principles in the U.S. and beyond. In 2016, Oprah Winfrey selected him as part of the SuperSoul100, recognizing him as one of the nation's leading entrepreneurs. Jeff's latest book, "Good Stress: The Health Benefits of Doing Hard Things," co-authored with his wife, Schuyler Grant, is set to be released on March 25, 2025. I've had the opportunity to read the galley and it's a terrific book that will open a lot of doors for each and every one of you in terms of regaining your health. TIMESTAMPS 00:00 Introduction and Personal Connection with Jeff Regarding the Los Angeles Wildfires 8:51 Introducing Jeff’s Book, Good Stress: The Health Benefits of Doing Hard Things 13:42 The Personal and Societal Costs of Poor Health 18:27 Jeff’s Background and Personal Approach to Wellness 22:54 Homeostasis as the Foundation of Health 25:42 Rethinking "Normal"—The Flaws of the Bell Curve Perspective 29:24 Evolutionary Perspectives on Health and Adaptation 34:55 Thermoregulation as a Pathway to Homeostatic Flexibility 38:15 Hypoxia and Its Role in Physiological Adaptation 47:04 The Therapeutic Potential of Thermal Shock 49:51 The Concept of Good Stress and the Evolutionary Mismatch of Modern Lifestyles 55:01 Optimal Timing and Approaches for Cold Plunging 1:00:46 Jeff’s Personal Biohacking Journey 1:07:08 Exploring the Benefits of Light Therapy and the Revival of Raw Milk Consumption ==== Jeff Krasno is the co-founder and CEO of Commune, a masterclass platform for personal and societal well-being and co-creator of Wanderlust, a global series of wellness events. He hosts the Commune podcast, interviewing a wide variety of luminaries from Deepak Chopra and Marianne Williamson to Matthew McConaughey and Gabor Maté. His latest venture expands Jeff’s personal story and protocols into a book, Good Stress: The Benefits of Doing Hard Things (Hay House, March 2025). The book dives deeper into the concepts from the course, distilling insights from over 400 podcast conversations Jeff has conducted, along with his personal experiences applying these ideas to transform his own health. It explores deliberate, self-imposed behaviors that promote social, psychological, and physical well-being, offering both a philosophical exploration of true wellness and practical steps to achieve it. Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our...

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 We all know that exercise is good for the body and specifically, very good for the brain. In fact, exercise is the most important inroad to better brain health, better brain function, protecting the brain against decline, and even with respect to mood issues like depression. But it's reasonable to ask how in fact does this work? How is it that exercising muscles does good things for the brain? On today's episode of the Empowering Neurologist we spent time with Dr. Austin Perlmutter. He takes us on a deep dive exploring the exact connection between muscle and its endocrine function in terms of creating various chemicals that are so helpful for better brain health. It's a great discussion that looks at things like how much exercise is appropriate, what type of exercise is best, how much protein we should be consuming, and what other supplements will augment the benefits of exercise in terms of better brain health. I think you will really enjoy this episode. I know I sure did, after all, getting to spend time with my son is always special! ===== 00:00:00 Introduction & Welcoming Dr. Austin 00:01:56 The Relationship of Muscle Health, Mental Health, and Brain Health 00:09:15 The Power of Exercise to Improve Cognition vs Pharmaceuticals & The Muscle as an Endocrine Organ 00:16:36 The Molecules Produced by Muscles: Myokines 00:20:10 Myokines, Inflammation, and Metabolic Health 00:26:43 Sarcopenia and The Risk of Dementia 00:31:50 Brain Derived Neurotropic Factor, Neuroplasticity & Weight Training 00:39:40 Animal versus Plant Protein to Build Healthy Muscle 00:46:26 Cycling Anabolic and Catabolic States 00:51:31 Why Women Are 2x More Likely to Develop Alzheimer's and What Supplementation Is Necessary to Compliment Building Muscle 01:05:40 Conclusion and Wrap Up ===== Dr. Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, researcher, educator, podcaster and entrepreneur. His mission is to help people get their brains unstuck for better mental and cognitive health. Dr. Perlmutter’s work on how environment and diet influences brain health has been featured on PBS, Rolling Stone, Newsweek, NPR, Fox, CBS and other top media outlets. He has co-produced and hosted some of the world’s largest online brain health events including Alzheimer’s, the Science of Prevention and the Better Brain Blueprint. He is the Managing Director of Big Bold Health, where he led a pioneering study exploring plant nutrient effects on human aging. He is the CEO of Lichen Air, which provides science-backed indoor air solutions for better brain health and longevity. He is also a research consultant to the Helfgott Research Institute, where he studies the epigenetic, metabolic, microbiome and immune effects of ayahuasca. Website: https://www.austinperlmutter.com/ YouTube: https://www.youtube.com/@draustinperlmutter IG: https: https://www.instagram.com/draustinperlmutter/ Lichen AIr: https://lichenair.com/ Dr. Austin Perlmutter's Muscle-Brain eGuide: https://www.austinperlmutter.com/muscleguide ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Over the last several decades, it’s been interesting to watch the progression of ideas for treating Alzheimer’s change from focusing on brain chemistry to targeting the accumulation of proteins in the brain associated with the disease. Recently, there’s been exciting interest in studying how the brain’s electrical circuits and rhythms change in Alzheimer’s and other brain degenerative disorders. The human brain operates in rhythms, with gamma frequencies playing a critical role in cognitive functions such as memory, attention, and learning. In neurodegenerative diseases like Alzheimer’s, these gamma oscillations are disrupted, contributing to the accumulation of harmful proteins such as amyloid-beta and tau. Cognito Therapeutics has developed a pioneering approach using non-invasive light and sound stimulation to restore these rhythms and trigger natural mechanisms for clearing these toxic proteins. In preclinical and early clinical trials, this method has demonstrated remarkable potential. By stimulating gamma oscillations, the therapy has shown the ability to reduce inflammation, enhance synaptic function, and activate microglia—immune cells responsible for clearing debris and maintaining brain health. For families battling cognitive decline, these results offer hope for improving quality of life and potentially slowing disease progression. Cognito’s research focuses on safety, accessibility, and scalability. Unlike pharmaceutical interventions, this approach avoids invasive procedures or systemic side effects, making it an attractive alternative or complementary treatment for Alzheimer’s. As the company advances its clinical trials, the implications extend far beyond Alzheimer’s. Cognito’s technology could pave the way for treatments for neurological conditions like Parkinson’s, MS, and traumatic brain injury. On our podcast today, we are joined by Christian Howell, CEO of Cognito Therapeutics. Howell is committed to advancing the understanding of brain health and delivering groundbreaking therapeutic solutions to improve patient outcomes. Under his leadership, Cognito Therapeutics has made significant strides in the development of gamma-frequency neuromodulation technologies, leveraging light and sound stimulation to address the mechanisms of Alzheimer’s and other neurodegenerative disorders. Howell is a strong advocate for translating cutting-edge research into real-world applications and has spearheaded the company’s efforts to validate its therapies through rigorous scientific studies and clinical trials. Howell holds advanced degrees in neuroscience and bioengineering and has dedicated his career to bridging the gap between scientific discovery and patient care. His work reflects a commitment to improving the lives of individuals and families impacted by cognitive decline and to shaping the future of brain health through innovation and collaboration. ==== 00:00 Introduction 00:59 Optogenetic Light & SoundTherapy 11:28 Innovations in Light and Sound Therapy at 40Hz Interval; Generating Neuroplasticity 17:48 Rethinking Alzheimer’s Treatment and Gamma Wave Stimulation’s Impact on Proteins 20:43 Overview of Cognito Therapeutics at Home Device 25:30 Usage for Therapeutic, Preventative, and Performance Enhancement. 28:37 Disease States: Dysregulation of Microglia; Long Covid, Chemo Brain, Sepsis 30:45: Breakthrough Designation from FDA For the Device 38:07 FDA Approval, Distribution, and Insurance Approval; Economic Burdens of Alzheimer’s 44:30 Closing Insights on Revolutionary Therapies ==== Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 After decades of stagnation, the field of psychiatry is undergoing a transformative shift. For 75 years, mental health issues were largely viewed as “chemical imbalances” best treated with medications. While these medications have helped many, their efficacy is often limited, and they come with common side effects like fatigue, weight gain, and sexual dysfunction. Enter metabolic psychiatry—a groundbreaking new approach that reimagines mental health challenges as issues rooted in brain metabolism. This fresh perspective is revolutionizing how we perceive and address mental health conditions, offering powerful, practical, and safe solutions that are accessible to everyone. The most exciting discovery of our time? Robust mental health is deeply connected to robust metabolic health—and achieving metabolic health starts with a brain-friendly diet. For those struggling with mental health, understanding how dietary changes can provide benefits that no medication can is critical. However, the key lies in making the right changes—ones that go beyond conventional dietary advice. By integrating cutting-edge research on brain metabolism with evidence-based insights on brain-nourishing foods, we can unlock a powerful formula for optimal mental well-being. This exciting synergy is the focus of our podcast, and today, we’re thrilled to feature an expert in this field: Dr. Georgia Ede, MD, author of Change Your Diet, Change Your Mind. In this episode, Dr. Ede shares her insights on the revolutionary potential of metabolic psychiatry and the role of diet in mental health. Together, we’ll explore how rethinking the way we nourish our brains can lead to profound changes in how we think, feel, and live. Join us for a deep dive into the intersection of nutrition and psychiatry and discover how small, actionable dietary changes can unlock a brighter, healthier future for your mind. ==== 0:05 Introduction 4:15 Welcoming Dr. Ede 5:01 Dr. Ede's Backstory And Experimenting with Her Own Diet 10:46 Shifting Beliefs From Standard Psychiatric Medicine 15:22 SSRI's And Their Efficacy 20:13 Standard American Diet And Widespread Mental Health Crisis 26:21 Inflammation And Its Affect On Mental Health 30:18 Insulin Resistance, The Brain, and Impact on Mental Health 34:49 The Pushback Georgie Has Received W 39:28 Metabolism, Mitochondrial Function Relation To Mental Health Issues 44:36 Using A Ketogenic Diet To Manage Mental Health 52:55 Personalized Medicine Through A Diet That Works For Your Body 1:01:20 Thank you to Dr. Georgia and Conclusion ==== Dr. Georgia Ede is an internationally recognized expert in nutritional and metabolic psychiatry. Her twenty-five years of clinical experience include twelve years at Smith College and Harvard University, where she was the first psychiatrist to offer students nutrition-based approaches to mental health conditions. Dr. Ede co-authored the first inpatient study of the ketogenic diet for serious mental illness, developed the first medically accredited course in ketogenic diets for mental health, and is a recipient of the Baszucki Brain Research Fund’s Metabolic Mind Award. Her bestselling new book Change Your Diet, Change Your Mind was recommended by the New York Times Book Review as among the three best mental health books of 2024. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Tune in to The Empowering Neurologist Podcast for an Inspiring Conversation with Dr. Jill Carnahan, Author of Unexpected I’ve just finished recording a very moving interview with Dr. Jill Carnahan—Functional Medicine expert, speaker, and author. This was an unforgettable conversation about her new book, Unexpected. Dr. Carnahan’s story is one of resilience, empathy, and transformation, and her insights have changed countless lives through her compassionate approach to health. Dr. Carnahan’s journey to becoming a functional medicine leader is anything but conventional. Early in her career, she faced serious health challenges that nearly ended her life and forever transformed her approach to patient care. After being diagnosed with breast cancer at just 25, Dr. Carnahan was forced to confront the fear, uncertainty, and upheaval that accompany life-altering illness. During her treatment, she developed a deeper understanding of what her patients were experiencing, not only physically but also emotionally. Just as she was beginning to regain her health, she was diagnosed with Crohn’s disease, a severe autoimmune disorder that impacted her life for years. These back-to-back health crises became defining moments for Dr. Carnahan. They pushed her to pursue holistic healing modalities, ultimately shifting her career path toward Functional Medicine. Through her own journey of recovery, she developed a unique perspective on health that goes beyond treating symptoms, instead focusing on addressing the root causes of illness and the interconnectedness of mind, body, and spirit. In our time together Dr. Carnahan discusses: ☑️ The pivotal moments in her life that led her to Functional Medicine and reshaped her philosophy on health ☑️ How emotional resilience and compassion are critical components of healing ☑️ Practical strategies to detoxify, restore gut health, and promote holistic recovery ☑️ Insights into managing autoimmunity and chronic illness in a way that prioritizes the whole person ☑️ The role of mindset and self-compassion in transforming personal health challenges into opportunities for growth My hope is that you will find our conversation to be an inspiring and enlightening experience. Her warmth, empathy, and expertise make her a true pioneer in Functional Medicine and a source of hope for anyone on their own health journey. ==== 00:11 Intro 01:09 Introduction to Dr. Jill 04:30 Dr. Jill’s Cancer Diagnosis 09:16 How She Learned To Trust Herself: Blending Intuition with Logic 11:54 The Illusion of Certainty & Embracing Fear 14:53 Returning to Medical School Post Chemo 20:12 Where Jill’s Cancer May Have Originated 24:24 The Diet That Helped Dr. Jill’s Crohn’s, Colitis, SIBO and SIFO Flare Ups 34:51 Dr. Jill’s Journey Into Functional Medicine as a Doctor 39:45 Dr, Perlmutter Shares His Patient’s Gluten-Free Experience 41:11 Using The Human Genome in Functional & Integrative Medicine 50:00 How Personal Agency Impacts The Healing Process 51:50 Upstream From The Microbiome Is The Soil & Outro ==== Dr. Jill Carnahan is Your Functional Medicine Expert® dually board certified in Family Medicine for 10 years and in Integrative Holistic Medicine. She is the founder and Medical Director of Flatiron Functional Medicine, a widely sought-after practice with a broad range of clinical services including functional medical consulting, chiropractic therapy, physical therapy, naturopathic medicine, acupuncture, and therapeutic massage. Be sure to follow her @drjillcarnahan on Instagram. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 What makes a good brain go bad? And if we can answer that question, how do we fix it? Of all the things that we consider that are important for brain cell function, the activity of the mitochondria is primary. And, what do mitochondria need to function at their best? The answer is not a supplement. It's not other forms of nutrients, it is oxygen. And as it turns out, enhancing, the oxygen availability for mitochondria is a powerful therapeutic tool across a wide variety of neurological issues. Mitochondrial dysfunction is central to things like dementia, autism, stroke, head injury, and even long COVID. Hyperbaric oxygen is a clearly the most leading edge therapy that targets mitochondrial function and improves blood supply to the brain. This is a technique in which individuals are placed in a chamber, the atmospheric pressure is increased, and they breathe oxygen in varying concentrations through a facemask. Today we are going to visit the Aviv Clinic in central Florida as I am joined by Amir Hadanny, MD, PhD, Aviv’s Chief Medical Officer and Head of Research. Dr. Hadanny has done and continues to do incredible research using hyperbaric oxygen therapy as an interventional tool to treat a variety of issues, including those mentioned above. The results, that are published in preview journals, are outstanding. Clearly hyperbaric oxygen therapy, when provided with a regimented protocol as we see at the Aviv Clinic, is giving people, a second chance. ==== 00:00 Intro 00:01:28 The Evolution of Hyperbaric Medicine Research 00:03:00 Clinical Applications: PTSD and Long COVID 00:05:30 Inside the Aviv Clinics Experience 00:09:22 Long COVID Study: Research Design and Findings 00:33:40 Cognitive and Physical Benefits in Healthy Aging 00:37:28 PTSD Breakthrough Study and Government Adoption 00:43:47 Future of Hyperbaric Medicine 00:45:50 Closing Remarks and Future Prospects ==== Amir Hadanny, MD, PhD is a neurosurgeon and researcher at Aviv Clinics, specializing in the use of hyperbaric medicine to optimize brain and body performance. He also serves as Chief Medical Officer and Head of Research at Aviv Scientific. Dr. Hadanny completed his MD at Tel Aviv University, his PhD in Bioinformatics and Computational Biology focused on machine learning from Bar Ilan University, and his neurosurgery training at Galilee Medical Center in Israel. He completed a Stereotactic and Functional Neurosurgery fellowship at Albany Medical Center and a Harvard Research Fellowship in the Brain Modulation Lab at Massachusetts General Hospital. Through his work at Aviv Clinics and Aviv Scientific, Dr. Hadanny has published more than 60 scientific studies on the use of a unique hyperbaric oxygen therapy protocol for neurorehabilitation and recovery in different brain pathologies and its effect on the biology of aging. https://www.nature.com/articles/s41598-022-15565-0 https://pubmed.ncbi.nlm.nih.gov/38360929/#:~:text=The%20results%20indicate%20HBOT%20can,after%20the%20last%20HBOT%20session. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 We are certainly all aware of the health consequences associated with consumption of ultra processed foods. And this discussion always moves to the role of the sugars and refined carbohydrates in these foods in terms of threatening our metabolic health - and rightfully so. But there’s another threat associated with these and other foods that is equally important. And that’s the type of oils they contain. In this episode of The Empowering Neurologist, I’m thrilled to welcome Dr. Cate Shanahan, a groundbreaking physician and the author of the eye-opening book Dark Calories. Dr. Shanahan dives deep into a topic that is often overlooked in conversations about nutrition: the dangers of seed oils and their pervasive presence in our diets. In Dark Calories, Dr. Shanahan reveals how seed oils—despite being marketed as healthy alternatives—can have detrimental effects on our brain and overall health. We explore the science behind these oils, explaining how they can lead to inflammation, oxidative stress, and toxicity, and how these mechanisms threaten our health. By bringing awareness to the hidden dangers of these ubiquitous ingredients, Dr. Shanahan encourages us to reconsider what we think we know about healthy eating. What makes this episode truly valuable is not just the scientific insights Dr. Shanahan shares but also the wealth of actionable material she provides. Throughout our conversation, we discuss practical steps listeners can take to reduce seed oil consumption and make healthier food choices. From understanding food labels to selecting healthier cooking fats, Dr. Shanahan equips us with the tools we need to nourish our bodies and brains effectively. She emphasizes the importance of whole, nutrient-dense foods, urging us to prioritize traditional fats over industrial seed oils that can contribute to chronic inflammation and cognitive decline. Whether you’re a health enthusiast or simply looking to improve your diet, this episode is packed with invaluable tips, like what to order when you go out to eat, that you can implement immediately. ==== 00:00 Introduction to Cate + the Dangers of Seed Oils 03:18 The 'Hateful Eight' Oils Explained 06:20 Origins of Vegetable Oils in the Food Supply 10:47 Toxicity of Refined Oils 15:03 Health Risks of Heated Oils 18:01 Medical Industry Conflicts 32:12 Strategies for Avoiding Harmful Oils 37:03 Comparison of Saturated vs. Unsaturated Fats 40:35 Impact of Toxic Oils on Chronic Diseases 53:00 Summary and Closing Out ==== Cate Shanahan, MD, has shaped the best parts of today’s food and health landscapes. Her books and other publications have taught a generation of health influencers what an ideal human diet looks like and the damaging effects of a collection of 8 common seed oils (“The Hateful 8”), informing the full spectrum of nutrition leaders, including keto, carnivore, functional medicine and more. Her science backed diet advice has inspired food entrepreneurs to make billions, including bone broth, live-culture ferments, and seed-oil-free business empires like the Primal Kitchen and Bulletproof brands. As a family physician, she has personally worked 1:1 with thousands of patients to improve energy metabolism and reduce fatigue, cellular inflammation, and organ dysfunction. Through her works and influence, she has helped millions escape the vicious cycle of sickness and drug dependence. Dr. Cate’s Monthly Newsletter signup: https://drcate.com/newsletter-signup/ About Dr. Cate’s Books https://drcate.com/which-drcate-book-should-i-buy/ LinkedIn: @DrCateShanahan X: @DrCateShanahan Instagram: @DrCateShanahan ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our...

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 What can we do to improve our brains? This is clearly a topic that is central to our messaging. And we have focused on a variety of levers to pull, including exercise, sleep, dietary changes, nature, connection, etc. But we've now learned about a powerful input that has proven incredibly effective in improving brain function, especially in a variety pathological situations like cognitive decline, anorexia, depression, and even autism. This innovative approach has been called olfactory enrichment. And basically, this involves stimulating the brain with various types of scents. Perhaps the top researcher on the planet exploring this subject and creating innovative ways for us to take advantage of olfactory enrichment is Dr. Michael Leon.He received his PhD from the University of Chicago and joined the professoriate at the young age of 24. He is currently Professor emeritus in the Department of Neurobiology and Behavior at the University of California Irvine. He has received the Research Scientist Development Award from the National Institute for Mental Health for his work on the neurobiology of early learning, the D.G. Marquis Award from the American Psychological Association for developing an effective treatment for children with autism, and the Healthcare Technology Acceleration Award from the California HealthCare Foundation for his work on body weight normalization. In a recent analysis from the Stanford University, he was ranked among the top 2% of scientists in the world. On the podcast we review this empowering science in detail and I am certain you will be you captivated by the therapeutic potential of this intervention.Also, we’ll explore the device Dr. Leon has created so that everyone can take advantage of these exciting developments. ==== 0:00 Intro 2:48 Researching Olfactory Enrichment 7:25 Impact of Olfaction on Disease 13:47 Relationship Between Inflammation & Sense of Smell 16:27 Study of Olfactory & Memory Loss 19:41 Losing Sense of Smell In Covid 24:01 Relationship of Taste to Olfaction 26:04 Impact on Depression 27:26 Difference Between this and Aromatherapy 31:59 Treating Anorexia with This 33:11 How This Works on a Subconscious Level 34:50 Memory Air Device 36:25 Conclusion ==== Michael Leon received his PhD from the University of Chicago and joined the professoriate at the age of 24. He is currently Professor emeritus (recalled) in the Department of Neurobiology and Behavior at the University of California Irvine. He also is a member of the Center for the Neurobiology of Learning and Memory, as well as the Institute for Memory Impairments and Neurological Disorders at UCI. He has received multiple awards for teaching undergraduates, including the Professor of the Year Award as the best teacher on the UCI campus. He has received the Research Scientist Development Award from the National Institute for Mental Health for his work on the neurobiology of early learning, the D.G. Marquis Award from the American Psychological Association for developing an effective treatment for children with autism, and the Healthcare Technology Acceleration Award, from the California HealthCare Foundation, Booz Allen Hamilton, and the Robert Wood Johnson Foundation for his work on body weight control. In a recent analysis from the Stanford University School of Medicine, he was ranked among the top 2% of scientists in the world for the impact of his research. He is a partner in Science Lab 3 and the Mando Group. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Our lifestyle choices are fundamental as it relates to the health of our brains. Who knew? Well one person who knows this information and has done an amazing job getting this out to public awareness is Louisa Nicola, neurophysiologist, human performance coach and founder of Neuro Athletics, a human performance coaching firm that supports the highest performing athletes and executives in the world. This organization bring science-based solutions to elite performers who want to perform at their highest level. Luisa graduated from the university of Sydney medical school and specializes in Neurophysiology. She is currently completing her PhD and has recently published fascinating report on the benefits of resistance exercises as it relates to Alzheimer's disease. The podcast that you were about to watch extremely empowering. What you will find in Louisa’s messaging is a heartfelt devotion to empowerment for all who will listen that truly, our brain’s destiny is something we can control. I'm very grateful that she joined us on the podcast today. ==== 0:00 Intro 2:37 How Louisa Got Started 5:00 Exercise’s Impact on Brain Health 11:37 Aerobics vs Strength Training 14:56 Wearable Devices to Track Exercise 19:53 What Happens in the Brain During Exercise 25:11 Importance of Restorative Sleep 30:42 Best Type of Diet for the Brain 33:09 Phd: Resistance Training & Alzheimer’s 36:28 Conclusion ==== Neurophysiologist and human performance coach, Louisa Nicola is the founder and head performance advisor of Neuro Athletics - a human performance coaching firm that boasts the highest performing athletes and executives in the world. Neuro Athletics brings science based solutions to elite performers who want to perform at their peak. Louisa graduated from the University of Sydney Medical School and specialises in neurophysiology. https://www.instagram.com/louisanicola_/ https://apple.co/3H02jPa https://neuroathletics.substack.com/subscribe https://www.neuroathletics.com.au/ ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Around 60 million people around the world have dementia. 300 million have depression, and billions of people are experiencing brain problems due to chronic stress. These conditions are partially preventable, but most people don’t know the steps to take to decrease their risk and protect their brains. It turns out that the place where our brains are at the highest risk for being damaged is actually in our homes, and that we have an incredible amount of control over what happens here. But sadly, most of us are being unintentionally exposed to things in our houses that are poisoning our brain health. In this episode, we’re going deep into the science that examines those factors in our environments that are damaging our brains. We connect with an expert in environmental and lifestyle medicine, Dr. Austin Perlmutter. We’re going to explore exactly what we are exposing ourselves to, in our homes, cars and offices, that threaten to worsen our cognitive and mental health. And, importantly, Dr. Perlmutter will reveal simple steps we can employ, today, to reduce this threat. ==== 0:00 Intro 3:06 How our environment threatens our brain 8:18 Health Begins in the Kitchen 12:10 Air Pollution in the Kitchen 18:13 Pollution in our World Today 23:23 Hidden Sources of Pollution: Vacuums & Incense 28:34 Effectiveness of N95 Masks 31:00 We Can’t Overlook This 35:00 Air Fresheners & Perfumes 39:13 Indoor Filtration & Ventilation 46:40 Other Pollutants to Watch Out For 49:25 Conclusion ==== Here's more about our guest, and yes, my son: Dr. Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, published researcher and international educator. His mission is to help people improve their health by targeting the biological basis of “stuckness” in our brains and bodies. His writings, presentations, podcasts, and online educational programs explore how environmental factors influence our cognitive and mental state and have reached millions. Dr. Perlmutter has been featured on PBS, Rolling Stone, MedPage today, Newsweek, Medical News Today, NPR and a wide range of other media outlets. He is a co-producer of the Alzheimer’s, the Science of Prevention series, and host of the Better Brain Blueprint series. Dr. Perlmutter currently serves as the managing director at Big Bold Health, a food-as-medicine company focused on helping people rejuvenate health through better immune function, where he is running a first-of-its kind study exploring the effects of plant nutrients on human aging through epigenetic modulation. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1